Southern Region Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*

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Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favourite city with Southern Region travellers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top vacation destinations in Southern Region

A cityscape at dusk with a prominent building in the center, surrounded by residential areas and a mountain in the background.
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Blantyre

Blantyre

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

4.5 out of 5
2 Hannover Avenue Blantyre
Fully refundableReserve now, pay when you stay
The price is CA $218 per night from Dec 4 to Dec 5
CA $218
CA $259 total
Dec 4 - Dec 5
includes taxes & fees
9/10 Wonderful! (156 reviews)
"Good location,clean,conveniente"

Reviewed on Oct 7, 2026

Protea Hotel by Marriott Blantyre Ryalls
Casa Mia

Casa Mia

3 out of 5
Kabula Hill Road Blantyre
The price is CA $139 per night from Nov 4 to Nov 5
CA $139
CA $165 total
Nov 4 - Nov 5
includes taxes & fees
8.6/10 Excellent! (129 reviews)
"Staff was excellent. Breakfast was a bit sparse. Rooms were comfortable. Location was a bit far from CBD, not walkable at night."

Reviewed on Oct 23, 2026

Casa Mia
Amaryllis Hotel

Amaryllis Hotel

5 out of 5
2 Laws Rd Blantyre Southern Region
Fully refundableReserve now, pay when you stay
The price is CA $245 per night from Nov 4 to Nov 5
CA $245
CA $290 total
Nov 4 - Nov 5
includes taxes & fees
6.4/10 (7 reviews)
"What a waste of good money. This is such an overrated hotel. It is ridiculously expensive. I had to change rooms in the middle of the night due to ongoing construction past 10pm. The breakfast buffet is $40 usd, in the states it would be $18 max (I’m American). The airport shuttle is $60 and it seemed ..."

Reviewed on Oct 29, 2026

Amaryllis Hotel
See all 104 properties in Southern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Southern Region vacation package cost?
Choose from any combination of flights, hotels and car rentals, and you can be vacationing in Southern Region from just . And the more you bundle, the more cash you save. Your dream vacation has never been so affordable.
How do I get a cheap travel package to Southern Region?
Our Southern Region vacation packages mean plenty of savings for the savvy traveler. For the best deals, simply bundle your flights, hotels and extras (such as activities) into one neat package. But low prices are just the beginning of your next big adventure. Book with Expedia and and you'll have over 550 air carriers and 1,000,000 hotel options all over the world to choose from. Whatever your budget or style, there's a vacation package to suit you.
What are the top hotels in Southern Region?
When it comes to properties in Blantyre, Protea Hotel by Marriott Blantyre Ryalls and Malawi Sun Hotel & Conference Centre are two fantastic options. If you're also spending time in Mangochi, Casa Mia and Hotel Victoria will make you feel at home.
How far in advance should I book my Southern Region vacation?
It's always wise to book early. Air carriers usually advertise flight tickets up to 12 months ahead of departure, and this is an ideal opportunity to pick up some of the lowest prices. Just been told you need to take all your vacation days in a few weeks? Don't fret. Expedia are never short of fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Southern Region travel package include?
Choose from a combination of hotels, flights and rental cars. Once you've made your booking, you can add experiences and tours. Want to pick your airfare class? That's easily done too. The choice is all yours when it comes to organizing your ideal Southern Region getaway.
What should I know before booking a Southern Region travel package?
A package can be easier on the bank balance than individually booking all you need for your trip. For example, bundle your hotels, flights and rental cars and score impressive savings. Whatever your vacation goals are, you're bound to find a package that matches your budget.
Can I choose my airline with a Southern Region Expedia vacation package?
You can. We offer more than 550 airline partners around the world, so fly with the carrier that suits your needs.
If I'm not able to travel, can I cancel my Southern Region vacation package?
If your travel plans in Southern Region have been upended, it's good to know that it's possible to cancel your booking. If you made your booking less than 24 hours ago, you may be able to receive a refund. If your booking is older than that, your airline, hotel or car rental company may impose fees. For more details, visit our Customer Service Portal.

Stay near popular Southern Region attractions

Monkey Bay Beach

8.6/10 (4 reviews)
If a restful vacation is part of your travel plans, Monkey Bay Beach might be the perfect place to seek out during your trip to Mangochi. Take in the museums while you're in the area.
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What to do in Southern Region

Malape Pillars Cultural Tour Liwonde

Malape Pillars Cultural Tour Liwonde

CA $40
per adult
Malape Pillars Cultural Tour Liwonde
Finished Product! Some of the food you can make!

Malawian Cooking Class with Experienced Local Chef

CA $35
per adult
Malawian Cooking Class with Experienced Local Chef
Hikers try climbing a rock on a tour

Zomba plateau Day Hike Tour

CA $226
per adult
Zomba plateau Day Hike Tour
See all activities in Southern Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.